There are a lot of very popular hosting control panels but they do not all offer efficient enterprise support. If you’re working in an enterprise web hosting environment you might want to have a look at ISPconfig, however. A lot of people already are: the hosting control panel is seeing 40,000 downloads every month, according to ISPconfig.
Installing ISPconfig is not yet as straight forward as it should be because some installation steps require manual intervention which can prove difficult for some people. However, ISPconfig can take care of most of the typical web hosting tasks you’d want, including management of web and FTP servers, plus the ability to handle mail and the option to manage SSH servers.